Glut 1, S-100, and Nerve Bundle Study in Vascular Anomalies

Abstract Vascular anomalies grouped into vascular tumors (hemangioma) (HI) and malformation (VM) are benign lesions that difficult to distinguish from one another clinically often confused with each other at histopathology. This confusing terminology leads improper diagnosis, illogical treatment, misdirected research. study aimed GLUT 1, S-100, nerve bundle differentiate hemangioma malformation. Thirty two cases of (26 malformations 6 hemangiomas) were taken the study. For histological evaluation immunohistochemistry (IHC), samples collected in formalin. All hematoxylin eosin-stained slides evaluated under light microscope for histology bundles. Immunohistochemical staining was performed by streptavidin–biotin method 1 S-100. positive all hemangiomas (100%) only case Nerve present 24 (92.3%) out 26 but not any S-100 found hemangioma. So expression, presence can help